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Friday, February 15, 2008

Researchers study genes, lifestyle causes of obesity

Andrew Cross, Daily Vidette Staff

A British study on obesity in twins attempted to put an end to the ongoing debate of nature versus nurture.

Researchers under the direction of Jane Wardle, the director of Cancer Research UK's Health Behavior Centre, examined the role genes and lifestyle choices play in causing individuals to become overweight.

The study determined that changes in the waist circumference and body mass index of children are largely caused by genetic factors.

The researchers examined over 5,000 pairs of twins before making the claim that weight gain is 77 percent attributable to genetics and only 23 percent caused by environmental aspects.

But many experts believe obesity can be attributed mostly to lifestyle factors.

From 1960 to 2000, the percentage of obese men and women in the United States has more than doubled. Obesity in children has more than tripled.

"This change happened too quickly to be genetic," Jim Hill, professor of pediatrics and medicine at the University of Colorado Health Sciences Center in Denver, said.

"The average American gains one to two pounds each year and has done so since about 1980. This is not genetics, but more likely the impact of the environment," Hill continued.

"Our genes are permissive in the sense that in an environment such as ours, our biology does not strongly oppose weight gain," Hill said.

The United States Surgeon General reports that about 300,000 deaths per year are obesity related.

According to Hill, "the environment…is the major cause of the obesity epidemic."

Past studies have shown that the weight gain of adopted children more closely follows that of the biological, not adoptive, parents. Studies tracking weight gain in twins often yield similar results.

Still, many experts point to lifestyle changes-increased consumption of high-fat foods and a lack of exercise-for the sudden explosion in obesity.

"The extra energy that is stored in the body as one becomes obese comes from eating too much and moving too little," Robert Cullen, assistant professor of family and consumer science, said.

"The surplus intake of calories versus the calories required for activity are deposited as body fat and lead to obesity," Cullen added.

If the experts agree on one thing, it is that proper eating habits and sufficient exercise is the key to maintaining a healthy body weight.

Labels: Health Article, News

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More Sleep, Less Childhood Obesity

kimping on Sleep May Make Children More Likely to Become Overweight or Obese

By Miranda Hitti

WebMD Medical News

Getting more sleep may help children avoid becoming overweight or obese.

That's according to a new review of 17 studies on sleep and childhood obesity.

The studies stretched from Europe to the U.S. to Asia. And around the world, the pattern was the same: Kids who didn't sleep enough were more likely to be overweight or obese.

Reviewer Youfa Wang, MD, PhD, an associate professor in the Center for Human Nutrition at Johns Hopkins University's Bloomberg School of Public Health, offers these tips for parents:

Remove the TV, computer, and video games from kids' bedrooms. "Therefore, children can have more time to sleep rather than be tempted to engage in these activities," Wang tells WebMD.
Set earlier bedtimes for kids. Wang suggests reading to young kids to help them get to sleep earlier.
Beat the morning rush by preparing the night before. That way, the whole family can sleep a little bit later.
Be a good role model for diet and exercise -- childhood obesity isn't just about sleep.

The review appears in February's edition of Obesity.

Children's Sleep: How Much Is Enough?

The new review used the following benchmarks for kids' sleep, including naps and nightly sleep, during a typical day:

Younger than 5: at least 11 hours
Ages 5-10: at least 10 hours
Ages 10 and older: at least 9 hours

Those thresholds, which are based on previous research, may not apply to everyone.

"Some people, because of their own biological differences or their quality of sleep, may need fewer hours of sleep than others," Wang tells WebMD.

Studying Childhood Obesity and Sleep

In the reviewed studies, parents reported how long their young kids slept. Adolescents reported their own sleep habits.

Wang's team pooled all that data and compared it to the children's BMI ( body mass index), which relates height to weight.

Compared with kids who got enough sleep, those who fell at least two hours short of the sleep benchmarks were almost twice as likely to be overweight or obese.

Children who missed the sleep benchmark by an hour were 58% more likely to be overweight or obese than kids who got enough sleep.

"For each hour increase in sleep, the risk of overweight/obesity was reduced on average by 9%," the researchers write.

Why the Findings?

The reviewed studies were observational, so it's not clear which came first: extra pounds or less sleep.

It's also not clear how sleep affects children's weight. But Wang notes several theories:

More time awake means more time to eat.
Less sleep at night makes for drowsier, less-active days (and fewer calories burned).
Sleep shortfalls may affect certain hormones. "This may increase people's feelings of hunger and also affect their energy expenditure," Wang says.

The links between sleep and BMI were stronger for boys than girls. The reason for that isn't clear, Wang says.

What About Genes?

That doesn't mean that other factors -- including genes, diet, and exercise -- aren't important. Just yesterday, another team of researchers noted heredity's influence on childhood obesity.

"I think people should be aware of all the important potential risk factors," Wang says.

He points out that genes may only have their full effect when the conditions are right -- and in the case of obesity genes, that might mean being in a setting ripe with opportunities to overeat.

"It's a coin; which side do you want to pay more attention to?" Wang asks, putting genes on one side of the coin and environmental factors on the flip side.

"I think from a public health perspective, people should pay more attention to environmental and behavioral factors," Wang says. He notes that gene tests and gene therapy aren't yet available for obesity. And though you can't change your genes, behavior can bend.

Labels: Health Article, News